A radioactive tracer, radiotracer , or radioactive label, is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tracing the path that the radioisotope follows from reactants to products. Radiolabeling or radiotracing is thus the radioactive form of isotopic …
radiotracer properties including absorption , distribution, metabolism, clearance and toxicity Development of automated procedures for the production of known radiotracers for campaigns of research (See Radiotracer production). Our capability includes the opportunity to undertake radiolabelling development of the following targets:, The radioactive tracers used most frequently are 123 I and 131 I. They provide information about the physiological handling of dietary iodine (127 I).Table I lists the clinically relevant nuclides of iodine and their specific uses. 123 I has ideal properties for nuclear imaging, emitting a gamma photon with an energy suited to gamma cameras. It has a half-life of 13 h, and scans can be made …
The PET radiotracer [1-11 C]glucose cannot be biochemically indistinguishable from glucose and therefore can follow the exact fate of glucose during the metabolism. This process releases cardiomyocyte as 11 CO2 and results in uptake, retention and disappearance of the radiotracer .
radiotracer , transport it to the experimental site and complete the measurements; and at the same time it should be short enough to minimize any environmental hazards. The selected radioisotope used for preparation of the radiotracer should have sufficiently high neutron absorption cross-section to enable its production in desired quantities.
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It should be stated at the outset that whereas much is known about the steps involved in each of these transport processes for calcium, much less is known with respect to most other minerals. … Stable strontium absorption as a measure of intestinal calcium absorption : comparison with the double- radiotracer calcium absorption test. Clin. Sci …
Studies on the enteric absorption of selenium in the chick using localized coccidial infections. Pesti GM, Combs GF Jr. Studies were conducted to determine the primary loci of gastrointestinal absorption of inorganic selenium in the chick using radiotracer techniques and Eimeria sp. infections of known site specificity for the gastrointestinal …
This review examines the evidence for quantitative SPECT and demonstrates clinical studies in which the accuracy of the reconstructed SPECT data has been assessed in vivo. SPECT reconstructions using CT-based compensation corrections readily achieve accuracy for 99mTc to within ±10% of the known concentration of the radiotracer in vivo.
